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Review
. 2004 Feb;16(1):61-7.
doi: 10.1016/j.ceb.2003.11.011.

Relating biochemistry and function in the myosin superfamily

Enrique M De La Cruz  1 , E Michael Ostap
Affiliations
Review

Relating biochemistry and function in the myosin superfamily

Enrique M De La Cruz et al. Curr Opin Cell Biol. 2004 Feb.

Abstract

All characterized myosins share a common ATPase mechanism. However, detailed kinetic analyses suggest that modulation of the rate and equilibrium constants that define the ATPase cycle confers specific properties to these motor proteins, suiting them to specific physiological tasks. Understanding the kinetic mechanisms allows potential cellular functions of the different myosin classes and isoforms to be better defined.

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