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. 2004 Mar 23;62(6):981-3.
doi: 10.1212/01.wnl.0000115394.90984.fd.

Reversible diffusion MRI abnormalities and transient mutism after liver transplantation

F Bianco  1 , F Fattapposta, N Locuratolo, A Pierallini, M Rossi, F Ruberto, L Bozzao
Affiliations

Reversible diffusion MRI abnormalities and transient mutism after liver transplantation

F Bianco et al. Neurology. .

Abstract

Transient mutism was observed in a liver transplant patient under immunosuppressant therapy with cyclosporine A and antifungal prophylaxis with amphotericin B. Fluid-attenuated inversion recovery and diffusion-weighted images revealed reversible bilateral symmetric hyperintensity located in the frontal motor cortex and corticospinal tracts. These MRI abnormalities may be caused by acute edema, possibly a combination of cytotoxic and vasogenic edema, which resolved with a prompt change in therapy.

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