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Review
. 2004 Feb;2(2):123-40.
doi: 10.1038/nrmicro818.

Pathogenic Escherichia coli

James B Kaper  1 , James P Nataro, Harry L Mobley
Affiliations
Review

Pathogenic Escherichia coli

James B Kaper et al. Nat Rev Microbiol. 2004 Feb.

Abstract

Few microorganisms are as versatile as Escherichia coli. An important member of the normal intestinal microflora of humans and other mammals, E. coli has also been widely exploited as a cloning host in recombinant DNA technology. But E. coli is more than just a laboratory workhorse or harmless intestinal inhabitant; it can also be a highly versatile, and frequently deadly, pathogen. Several different E. coli strains cause diverse intestinal and extraintestinal diseases by means of virulence factors that affect a wide range of cellular processes.

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