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Review
. 2004 Feb;5(2):110-20.
doi: 10.1038/nrm1309.

Sorting GPI-anchored proteins

Satyajit Mayor  1 , Howard Riezman
Affiliations
Review

Sorting GPI-anchored proteins

Satyajit Mayor et al. Nat Rev Mol Cell Biol. 2004 Feb.

Abstract

The study of glycosylphosphatidylinositol-anchored-protein sorting has led to some surprising new findings and concepts. Evidence is accumulating that, during their delivery to the surface, different types of plasma membrane protein might be sorted from each other early in this pathway, in the endoplasmic reticulum. Furthermore, membrane-lipid composition and microdomains might have a role in the process of protein sorting in both the secretory and endocytic pathways.

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