A touching picture of nicotinic binding
- PMID: 15046715
- DOI: 10.1016/s0896-6273(04)00151-5
A touching picture of nicotinic binding
Abstract
The snail acetylcholine binding protein (AChBP) is homologous to the extracellular domains of the nicotinic ACh receptors. In this issue of Neuron, Celie et al. show how the crystal structures of AChBP in complexes with carbamylcholine and nicotine reveal the basis for agonist recognition by ACh receptors.
Comment on
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Nicotine and carbamylcholine binding to nicotinic acetylcholine receptors as studied in AChBP crystal structures.Neuron. 2004 Mar 25;41(6):907-14. doi: 10.1016/s0896-6273(04)00115-1. Neuron. 2004. PMID: 15046723
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