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. 2004 Aug;25(18):4485-8.
doi: 10.1016/j.biomaterials.2003.11.007.

Apatite formation on non-woven fabric of carboxymethylated chitin in SBF

Tadashi Kokubo  1 , Masayuki Hanakawa, Masakazu Kawashita, Masahiko Minoda, Toshiyuki Beppu, Takeaki Miyamoto, Takashi Nakamura
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Apatite formation on non-woven fabric of carboxymethylated chitin in SBF

Tadashi Kokubo et al. Biomaterials. 2004 Aug.

Abstract

Chitin fibres constituting a non-woven fabric were carboxymethylated in monochloro acetic acid and treated with saturated Ca(OH)(2) aqueous solution. Within 3 days in a simulated body fluid with pH value and ion concentrations nearly equal to those of human blood plasma, a bonelike apatite layer formed on the surface of fibres of the treated fabric. The apatite-chitin fibre composite thus prepared is expected to be useful as a flexible bioactive bone-repairing material.

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