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. 2004 Apr;48(4):1361-4.
doi: 10.1128/AAC.48.4.1361-1364.2004.

Increasing prevalence of methicillin-resistant Staphylococcus aureus causing nosocomial infections at a university hospital in Taiwan from 1986 to 2001

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Increasing prevalence of methicillin-resistant Staphylococcus aureus causing nosocomial infections at a university hospital in Taiwan from 1986 to 2001

Po-Ren Hsueh et al. Antimicrob Agents Chemother. 2004 Apr.

Abstract

A rapid emergence of nosocomial methicillin-resistant Staphylococcus aureus (MRSA) infection (from 26.3% in 1986 to 77% in 2001) was found. The susceptibility of 200 nonduplicate blood isolates of MRSA and 100 MRSA isolates causing refractory bacteremia to 22 antimicrobial agents disclosed that glycopeptides, quinupristin-dalfopristin, and linezolid remained the most active agents.

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Figures

FIG. 1.
FIG. 1.
Incidence of nosocomial bloodstream infections caused by S. aureus and distribution of S. aureus among all pathogens causing nosocomial bloodstream infections at the NTUH, 1981 to 2001.
FIG. 2.
FIG. 2.
Association between the prevalence of oxacillin-resistant S. aureus (MRSA) causing nosocomial infections and annual consumption (defined daily dose [DDD] per 1,000 patient-days) of extended-spectrum cephalosporins (cefotaxime, ceftriaxone, ceftazidime, cefepime, and cefpirome), carbapenems (imipenem and meropenem), ciprofloxacin, and glycopeptides (vancomycin and teicoplanin) at the NTUH, 1986 to 2001.

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