Molecular pharmacology of calmodulin pathways in the cell functions

Abstract

In this paper we summarize much of the pharmacological evidence that has led to our current understanding of calmodulin-regulated cell function, with emphasis on aspects that may be relevant to drug design. These newly developed compounds are one of the most powerful tools as molecular probes for pharmacological approach, and will shed light on the physiological significance and molecular mechanisms of calmodulin-dependent pathways in various cell functions.