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. 1992 Jul;141(7):47-50.

[The clinical evaluation of the hypocholesterolemic effects of an inhibitor of cholesterol synthesis: mevalonic acid]

[Article in Italian]
E Del Nero  1 , N Aloe, C Augeri, F Avola, G Carta, A Cavagnaro, R De Grandi, M Gianfreda, G P Magro, G P Mazzarello, et al.
Affiliations
  • PMID: 1505176

[The clinical evaluation of the hypocholesterolemic effects of an inhibitor of cholesterol synthesis: mevalonic acid]

[Article in Italian]
E Del Nero et al. Clin Ter. 1992 Jul.

Abstract

Twenty eight patients with heterozygous familial hypercholesterolemia were treated with mevalonic acid (an inhibitor of cholesterol synthesis) for 45 days. Patients received a daily dose of 750 to 1500 mg mevalonic acid depending on plasma cholesterol levels. Results showed a significant reduction in cholesterol values whereas no significant difference was observed in HDL cholesterol and triglyceride levels.

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