Review
doi: 10.1385/1-59259-762-9:327.
Mammalian two-hybrid assay for detecting protein-protein interactions in vivo
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- PMID: 15064467
- DOI: 10.1385/1-59259-762-9:327
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Review
Mammalian two-hybrid assay for detecting protein-protein interactions in vivo
Methods Mol Biol.
2004.
Abstract
Mammalian two-hybrid assay is a convenient, powerful tool to investigate protein-protein interactions in vivo. In particular, this method has a major advantage over the better known yeast version in that one can study interactions between mammalian proteins that may not fold correctly in yeast or that require post-translational modification or external stimulation that are not present in yeast.
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