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Review
. 2004 Mar;6(3):319-27.
doi: 10.1016/j.micinf.2003.11.015.

Danger, death and DNA vaccines

Affiliations
Free article
Review

Danger, death and DNA vaccines

Elke S Bergmann-Leitner et al. Microbes Infect. 2004 Mar.
Free article

Abstract

DNA vaccines, although successful in many animal models of various diseases, remain insufficiently immunogenic in humans. Among the countless approaches to improve them is the stimulation of the innate immune system by promoting the apoptotic death of the transfected host cells, which is the focus of this review.

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