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Comment
. 2004 Mar;113(6):806-8.
doi: 10.1172/JCI21310.

Predicting the clinical course of prostate cancer

James McKiernan  1 , Mitchell C Benson
Affiliations
Comment

Predicting the clinical course of prostate cancer

James McKiernan et al. J Clin Invest. 2004 Mar.

Abstract

Risk stratification in prostate cancer remains a significant clinical challenge. A study in this issue of the JCI describes an exciting application of high-throughput functional genomic technology to further refine our understanding of treatment failure risk in prostate cancer patients.

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Figures

Figure 1
Figure 1
Prostate cancer is the second most common malignancy in men. The prostate gland (A) is located just below the male bladder and can undergo a period of growth beginning in middle age. Malignant tumors of glandular origin (B) are usually adenocarcinomas. Early detection is possible through annual digital rectal examinations and routine PSA testing. Glinksy et al. (4) use gene expression profiling to identify and test prognostic indicators for prostate cancer. The authors developed several genetic “signatures” able to discriminate recurrent versus nonrecurrent disease. Image copyright of Mayo Foundation for Medical Education and Research. All rights reserved. Used with permission from www.MayoClinic.com.
See this image and copyright information in PMC

Comment on

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