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. 2003;6(3-4):223-6.
doi: 10.1023/b:modi.0000006779.13561.12.

A novel one-pot, four component synthesis of some densely functionalized pyrroles

Javad Azizian  1 , Ali R Karimi, Hamedeh Arefrad, Ali A Mohammadi, M R Mohammadizadeh
Affiliations

A novel one-pot, four component synthesis of some densely functionalized pyrroles

Javad Azizian et al. Mol Divers. 2003.

Abstract

A new one-pot four component procedure for synthesis of densely functionalized pyrroles using commercially available ninhydrin with phosphorane intermediates produced in the reaction between triphenylphosphine, ammonium thiocyanate (or ammonium acetate) and various dialkyl acetylenedicarboxylates was developed.

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References

    1. Org Lett. 2000 Mar 9;2(5):709-12 - PubMed
    1. Angew Chem Int Ed Engl. 2000 Sep 15;39(18):3168-3210 - PubMed

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