Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2004 Jun 1;102(1):59-64.
doi: 10.1016/j.virusres.2004.01.016.

RNA interference against retroviruses

Wen-Yuan Hu  1 , Frederic D Bushman, Amara C Siva
Affiliations
Review

RNA interference against retroviruses

Wen-Yuan Hu et al. Virus Res. .

Abstract

Bang and Ellerman, and later Peyton Rous, reported the first identification of transmissible cancer-causing agents, which later turned out to be avian retroviruses. Today avian retroviruses are important models for study of retrovirus replication and pathogenesis, and also important pathogens of domestic fowl. Here we describe the use of RNA interference (RNAi) in live chick embryos to block replication of an avian retrovirus. We also describe inhibition of ASLV and HIV replication in cell culture with RNAi.

PubMed Disclaimer

Substances

LinkOut - more resources