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Case Reports
. 2004 Apr;42(4):1840-2.
doi: 10.1128/JCM.42.4.1840-1842.2004.

Problems in identification of Francisella philomiragia associated with fatal bacteremia in a patient with chronic granulomatous disease

A Friis-Møller  1 , L E Lemming, N H Valerius, B Bruun
Affiliations
Case Reports

Problems in identification of Francisella philomiragia associated with fatal bacteremia in a patient with chronic granulomatous disease

A Friis-Møller et al. J Clin Microbiol. 2004 Apr.

Abstract

Francisella philomiragia is a rare gram-negative, halophilic coccobacillus with bizarre spherical forms on primary isolation. A case of F. philomiragia bacteremia in a 24-year-old patient with chronic granulomatous disease is reported. Identification of F. philomiragia was problematic with conventional tests but was done correctly and rapidly by kit 16S ribosomal DNA sequencing.

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Figures

FIG. 1.
FIG. 1.
Alignment of the 16S rDNA sequences of F. philomiragia 1951 (GenBank AY496933), F. philomiragia ATCC 25015T (GenBank L26085), and F. tularensis ATCC 6223T (GenBank Z21931). Only regions with sequence variation are shown.
See this image and copyright information in PMC

References

    1. Forsman, M., G. Sandström, and A. Sjöstedt. 1994. Analysis of 16S ribosomal DNA sequences of Francisella strains and utilization for determination of the phylogeny of the genus and for identification of strains by PCR. Int. J. Syst. Bacteriol. 44:38-46. - PubMed
    1. Goldblatt, D., and A. J. Thrasher. 2000. Chronic granulomatous disease. Clin. Exp. Immunol. 122:1-9. - PMC - PubMed
    1. Hollis, D. G., R. E. Weaver, A. G. Steigerwalt, J. D. Wenger, C. W. Moss, and D. J. Brenner. 1989. Francisella philomiragia comb. nov. (formerly Yersinia philomiragia) and Francisella tularensis biogroup novicida (formerly Francisella novicida) associated with human disease. J. Clin. Microbiol. 27:1601-1608. - PMC - PubMed
    1. Jensen, W. J., C. R. Owen, and W. L. Jellison. 1969. Yersinia philomiragia sp. n., a new member of the Pasteurella group of bacteria, naturally pathogenic for the muskrat (Ondatra zibethica). J. Bacteriol. 100:1237-1241. - PMC - PubMed
    1. Johansson, A., A. Ibrahim, I. Göransson, U. Eriksson, D. Gurycova, J. E. Clarridge III, and A. Sjöstedt. 2000. Evaluation of PCR-based methods for discrimination of Francisella species and subspecies and development of a specific PCR that distinguishes the two major subspecies of Francisella tularensis. J. Clin. Microbiol. 38:4180-4185. - PMC - PubMed

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