Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2004 Jan;10(1):25-31.
doi: 10.3201/eid1001.030553.

Severe acute respiratory syndrome, Beijing, 2003

Affiliations

Severe acute respiratory syndrome, Beijing, 2003

Wannian Liang et al. Emerg Infect Dis. 2004 Jan.

Abstract

The largest outbreak of severe acute respiratory syndrome (SARS) struck Beijing in spring 2003. Multiple importations of SARS to Beijing initiated transmission in several healthcare facilities. Beijing's outbreak began March 5; by late April, daily hospital admissions for SARS exceeded 100 for several days; 2,521 cases of probable SARS occurred. Attack rates were highest in those 20-39 years of age; 1% of cases occurred in children <10 years. The case-fatality rate was highest among patients >65 years (27.7% vs. 4.8% for those 20-64 years, p < 0.001). Healthcare workers accounted for 16% of probable cases. The proportion of case-patients without known contact to a SARS patient increased significantly in May. Implementation of early detection, isolation, contact tracing, quarantine, triage of case-patients to designated SARS hospitals, and community mobilization ended the outbreak.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Epidemic curve—severe acute respiratory syndrome (SARS) probable case-patients by date of hospitalization and type of exposure, Beijing, 2003. Open bars indicate nonhealthcare workers without contact with a SARS patient; dark bars (“1.1”) indicate nonhealthcare workers with contact with a SARS patient; light filled bars indicate healthcare workers.
Figure 2
Figure 2
Clusters of severe acute respiratory syndrome (SARS) cases among healthcare workers in four hospitals, Beijing 2003.
Figure 3
Figure 3
Attack rates (cases per 100,000 population) by age and sex of probable severe acute respiratory syndrome (SARS), Beijing 2003.

References

    1. Drosten C, Gunther S, Preiser W, van der Werf S, Brodt H-R, Becker S, et al. Identification of a novel coronavirus in patients with severe acute respiratory syndrome. N Engl J Med. 2003;348:1967–76. 10.1056/NEJMoa030747 - DOI - PubMed
    1. Ksiazek TG, Erdman D, Goldsmith CS, Zaki SR, Peret T, Emery S, et al. A novel coronavirus associated with severe acute respiratory syndrome. N Engl J Med. 2003;348:1953–66. 10.1056/NEJMoa030781 - DOI - PubMed
    1. Peiris J, Lai S, Poon L, Guan Y, Yam LYC, Lim W, et al. Coronavirus as a possible cause of severe acute respiratory syndrome. Lancet. 2003;361:1319–25. 10.1016/S0140-6736(03)13077-2 - DOI - PMC - PubMed
    1. Tsang KW, Ho PL, Ooi GC, Yee WK, Wang T, Chan-Yeung M, et al. A cluster of cases of severe acute respiratory syndrome in Hong Kong. N Engl J Med. 2003;348:1977–85. 10.1056/NEJMoa030666 - DOI - PubMed
    1. Lee N, Hui D, Wu A, Chan P, Cameron P, Joynt GM, et al. A major outbreak of severe acute respiratory syndrome in Hong Kong. N Engl J Med. 2003;348:1986–94. 10.1056/NEJMoa030685 - DOI - PubMed

Publication types

MeSH terms

LinkOut - more resources