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. 2004 Apr 13;62(7):1206-9.
doi: 10.1212/01.wnl.0000119341.59445.cf.

Leukoencephalopathy, cerebral calcifications, and cysts: new observations

L M Nagae-Poetscher  1 , G Bibat, M Philippart, S Rosemberg, A Fatemi, M T C Lacerda, M O R Costa, F Kok, C Costa Leite, A Horská, P B Barker, S Naidu
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Leukoencephalopathy, cerebral calcifications, and cysts: new observations

L M Nagae-Poetscher et al. Neurology. .

Abstract

We describe three cases of the rare syndrome of leukoencephalopathy, brain calcifications, and cysts. Conventional MRI, proton spectroscopy, and diffusion-weighted imaging yielded additional information on the disease. Imaging findings favor increased water content rather than a demyelinating process in the pathophysiology of this disease. Clinical features of Coats disease and consanguinity were also encountered.

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