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Review
. 2004 Apr;15(2):126-31.
doi: 10.1016/j.copbio.2004.02.007.

Transgene integration in plants: poking or patching holes in promiscuous genomes?

David A Somers  1 , Irina Makarevitch
Affiliations
Review

Transgene integration in plants: poking or patching holes in promiscuous genomes?

David A Somers et al. Curr Opin Biotechnol. 2004 Apr.

Abstract

Transgene integration in plants transformed by either Agrobacterium or direct DNA delivery methods occurs through illegitimate recombination (IR). The precise mechanism(s) for IR-mediated transgene integration and the role of host double-strand break repair enzymes remain unknown. A recent wealth of sequenced transgene loci and investigations aimed at genetically dissecting transgene integration mechanism(s) have provided new insights into the process.

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