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Review
. 2004 Apr 16;117(2):149-51.
doi: 10.1016/s0092-8674(04)00340-x.

Driven to autoimmunity: the nod mouse

Alena M Gallegos  1 , Michael J Bevan
Affiliations
Free article
Review

Driven to autoimmunity: the nod mouse

Alena M Gallegos et al. Cell. .
Free article

Abstract

In the lymphoid system, T cells respond to space or under-crowding by dividing to maintain their numbers. In this issue of Cell, evidence is provided that this homeostatic proliferation, coupled with excess production of a cytokine, IL-21, is a key factor in susceptibility to autoimmune diabetes.

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