A supercode for inflammation
- PMID: 15084264
- DOI: 10.1016/s1074-7613(04)00083-4
A supercode for inflammation
Abstract
Siegelman and colleagues demonstrate unexpected synergism of CD44 and VLA-4 during lymphocyte extravasation. This is the first time that molecules mediating rolling and firm adhesion have been shown to associate biochemically leading to direct functional cooperation.
Comment on
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Bimolecular complex between rolling and firm adhesion receptors required for cell arrest; CD44 association with VLA-4 in T cell extravasation.Immunity. 2004 Apr;20(4):455-65. doi: 10.1016/s1074-7613(04)00077-9. Immunity. 2004. PMID: 15084274
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