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Review
. 2004 Apr;17(2):255-67.
doi: 10.1128/CMR.17.2.255-267.2004.

Candida infections of medical devices

Erna M Kojic  1 , Rabih O Darouiche
Affiliations
Review

Candida infections of medical devices

Erna M Kojic et al. Clin Microbiol Rev. 2004 Apr.

Abstract

The number of indwelling medical devices is escalating, and an increasing proportion of device-related infections are being caused by Candida spp. Candida spp. produce biofilms on synthetic materials, which facilitates adhesion of the organisms to devices and renders them relatively refractory to medical therapy. Management of device-related Candida infections can be challenging. Removal of the infected device is generally needed to establish cure of Candida infections of medical devices. However, since the pathogenesis of Candida bloodstream infection is complicated, more studies are necessary to determine the role of catheter exchange in patients with both gastrointestinal tract mucositis and indwelling catheters. The medical and economic impact of these infections is enormous.

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Figures

FIG. 1.
FIG. 1.
Scanning electron micrograph of a C. albicans biofilm that has formed in vitro on the surface of a vascular catheter. Reprinted from reference .
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