doi: 10.1023/b:bebm.0000024386.33789.0f.
Experimental Mycoplasma hominis infection of the genital tract in BALB/c mice
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- PMID: 15085246
- DOI: 10.1023/b:bebm.0000024386.33789.0f
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Experimental Mycoplasma hominis infection of the genital tract in BALB/c mice
Bull Exp Biol Med.
2004 Jan.
Abstract
We studied the ability of laboratory and clinical strains of Mycoplasma hominis to colonize the genital tract mucosa in BALB/c mice. Colonization with mycoplasma occurred only in mice receiving estrogen. Mycoplasma hominis strains obtained after 3-fold passage through the vaginal mucosa in mice and administered intravaginally in a dose of 0.5 x 10(8) CFU/ml caused infection in 100% animals. Inflammation in the lower genital tract was reduced by the 8th week after infection.
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