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. 2004 Jan;137(1):53-5.
doi: 10.1023/b:bebm.0000024386.33789.0f.

Experimental Mycoplasma hominis infection of the genital tract in BALB/c mice

M M Shkarupeta  1 , V N Lazarev, V M Govorun
Affiliations

Experimental Mycoplasma hominis infection of the genital tract in BALB/c mice

M M Shkarupeta et al. Bull Exp Biol Med. 2004 Jan.

Abstract

We studied the ability of laboratory and clinical strains of Mycoplasma hominis to colonize the genital tract mucosa in BALB/c mice. Colonization with mycoplasma occurred only in mice receiving estrogen. Mycoplasma hominis strains obtained after 3-fold passage through the vaginal mucosa in mice and administered intravaginally in a dose of 0.5 x 10(8) CFU/ml caused infection in 100% animals. Inflammation in the lower genital tract was reduced by the 8th week after infection.

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