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. 2004 Apr;15(3):237-41.
doi: 10.1023/B:CACO.0000024212.66334.26.

International trends in prostate-cancer mortality: the decrease is continuing and spreading

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International trends in prostate-cancer mortality: the decrease is continuing and spreading

P D Baade et al. Cancer Causes Control. 2004 Apr.

Abstract

Objective: To measure recent changes in prostate-cancer mortality across 24 developed countries.

Methods: Mortality data for men aged 50-79 years were obtained from the World Health Organisation mortality database and we assessed trends in age-standardised mortality rates using joinpoint regression models.

Results: Significant reductions in prostate-cancer mortality were observed in United Kingdom, United States, Austria, Canada, Italy, France, Germany, Australia and Spain, and downward trends were also observable in the Netherlands, Ireland and Sweden.

Conclusions: Mortality declines for prostate cancer are now evident in 12 out of the 24 developed countries considered in this analysis. Increases in PSA screening and better treatment of early-stage disease, possibly acting in combination, remain plausible hypotheses.

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