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. 2004 Apr 30;18(7):1043-9.
doi: 10.1097/00002030-200404300-00013.

Breastfeeding and maternal HIV-1 disease progression and mortality

Gilda Sedgh  1 , Donna Spiegelman, Ulla Larsen, Gernard Msamanga, Wafaie W Fawzi
Affiliations

Breastfeeding and maternal HIV-1 disease progression and mortality

Gilda Sedgh et al. AIDS. .

Abstract

Objective: To examine the association between breastfeeding and disease progression among HIV-infected women in Dar es Salaam, Tanzania.

Design and methods: Cohort study design with Cox proportional hazards models.

Results: The relative risk of death comparing women who recently had been breastfeeding to those who were not breastfeeding was 0.47 (95% confidence interval, 0.18-1.20). Neither breastfeeding status nor the duration of exclusive or partial breastfeeding was associated with HIV-1 disease progression, represented by death or development of a low CD4 cell count, anemia or excessive weight loss, in multivariate analyses. These associations remained insignificant when women with relatively low and high CD4 cell counts were analyzed separately.

Conclusion: There is insufficient evidence to support the hypothesis that breastfeeding is detrimental to the health of HIV-infected women.

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