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. 2000 Jun;1(2):156-72.
doi: 10.1046/j.1526-4637.2000.00022.x.

Sleep disturbance and nonmalignant chronic pain: a comprehensive review of the literature

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Sleep disturbance and nonmalignant chronic pain: a comprehensive review of the literature

L A Menefee et al. Pain Med. 2000 Jun.

Abstract

Sleep disturbance is an important clinical complaint for individuals with nonmalignant pain conditions. This review is a broad introduction to the literature on sleep disturbance and chronic pain conditions. The article critically reviews studies of sleep disturbance in musculoskeletal pain, arthritis, headache, and fibromyalgia. Current neurobiological hypotheses regarding the pathogenesis of sleep disturbance and chronic pain, common comorbid disorders, and pharmacologic and non-pharmacologic treatments for sleep disturbance are reviewed.

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