Diagnostic markers of infection in neonates
- PMID: 15102726
- PMCID: PMC1721679
- DOI: 10.1136/adc.2002.023838
Diagnostic markers of infection in neonates
Abstract
Diagnostic markers of infection are useful indicators of neonatal sepsis. Serial measurements of infection markers can improve diagnostic sensitivity, and the use of multiple markers can enhance diagnostic accuracy. Current evidence suggests that promising markers may be useful for early termination of antimicrobial treatment, but none of the current diagnostic tests are sensitive and specific enough to influence the clinical decision for withholding antibiotic treatment at the onset of suspected infection.
Similar articles
-
Diagnostic markers for neonatal sepsis.Curr Opin Pediatr. 2006 Apr;18(2):125-31. doi: 10.1097/01.mop.0000193293.87022.4c. Curr Opin Pediatr. 2006. PMID: 16601490 Review.
-
Immunologic biomarkers for diagnostic of early-onset neonatal sepsis.J Matern Fetal Neonatal Med. 2019 Jan;32(1):143-153. doi: 10.1080/14767058.2017.1366984. Epub 2017 Aug 31. J Matern Fetal Neonatal Med. 2019. PMID: 28797204 Review.
-
Diagnosis of late onset neonatal sepsis with cytokines, adhesion molecule, and C-reactive protein in preterm very low birthweight infants.Arch Dis Child Fetal Neonatal Ed. 1997 Nov;77(3):F221-7. doi: 10.1136/fn.77.3.f221. Arch Dis Child Fetal Neonatal Ed. 1997. PMID: 9462194 Free PMC article. Clinical Trial.
-
Potential biomarkers for effective screening of neonatal sepsis infections: An overview.Microb Pathog. 2017 Jun;107:234-242. doi: 10.1016/j.micpath.2017.03.042. Epub 2017 Apr 1. Microb Pathog. 2017. PMID: 28377234 Review.
-
Diagnostic tests in neonatal sepsis.Curr Opin Infect Dis. 2008 Jun;21(3):223-7. doi: 10.1097/QCO.0b013e3282fa15dd. Curr Opin Infect Dis. 2008. PMID: 18448965 Review.
Cited by
-
Study on the usefulness of APR scores from the viewpoint of proinflammatory cytokines.Dis Markers. 2015;2015:981981. doi: 10.1155/2015/981981. Epub 2015 Jan 15. Dis Markers. 2015. PMID: 25667565 Free PMC article.
-
The host response to sepsis and developmental impact.Pediatrics. 2010 May;125(5):1031-41. doi: 10.1542/peds.2009-3301. Epub 2010 Apr 26. Pediatrics. 2010. PMID: 20421258 Free PMC article. Review.
-
Emerging biomarkers for the diagnosis of severe neonatal infections applicable to low resource settings.J Glob Health. 2011 Dec;1(2):210-23. J Glob Health. 2011. PMID: 23198120 Free PMC article.
-
Introducing heart rate variability monitoring combined with biomarker screening into a level IV NICU: a prospective implementation study.Eur J Pediatr. 2022 Sep;181(9):3331-3338. doi: 10.1007/s00431-022-04534-4. Epub 2022 Jul 4. Eur J Pediatr. 2022. PMID: 35786750 Free PMC article.
-
Evaluation of serum interleukins-6, 8 and 10 levels as diagnostic markers of neonatal infection and possibility of mortality.Iran J Basic Med Sci. 2013 Dec;16(12):1232-7. Iran J Basic Med Sci. 2013. PMID: 24570828 Free PMC article.
References
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical