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Review
. 2004 Mar;78(3):503-12.
doi: 10.1016/j.exer.2003.07.003.

The organization of collagen in the corneal stroma

Affiliations
Review

The organization of collagen in the corneal stroma

Keith M Meek et al. Exp Eye Res. 2004 Mar.

Abstract

The cornea has evolved to fulfil the dual functions of enclosing and protecting the inner contents of the eye, and focussing light onto the retina with minimum scatter and optical degradation. It does this by means of the arrangement of the constituent collagen fibrils, an arrangement that is unique in connective tissues. This article reviews our current knowledge about the detailed organization of collagen in the corneal stroma, and presents new data suggesting that a significant proportion of collagen fibrils running across the cornea, change direction near the limbus and fuse with the circumferential limbal collagen.

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