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Review
. 1992 Aug;13(8):306-14.
doi: 10.1016/0167-5699(92)90043-7.

VDJ recombination

F W Alt, E M Oltz, F Young, J Gorman, G Taccioli, J Chen
Review

VDJ recombination

F W Alt et al. Immunol Today. 1992 Aug.

Abstract

The ability of lymphocyte receptor V, D and J gene segments to rearrange generates much of the receptor diversity that is the hallmark of the immune system. Naturally, the mechanisms of immunoglobulin and T-cell receptor gene recombination are of enormous interest. Here, Fred Alt and colleagues review current understanding of the process and speculate on future findings.

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