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Review
. 2004 Apr;6(5):501-12.
doi: 10.1016/j.micinf.2004.01.006.

The role of mhc polymorphism in anti-microbial resistance

Janko Nikolich-Zugich  1 , Daved H Fremont, Michael J Miley, Ilhem Messaoudi
Affiliations
Free article
Review

The role of mhc polymorphism in anti-microbial resistance

Janko Nikolich-Zugich et al. Microbes Infect. 2004 Apr.
Free article

Abstract

The major histocompatibility complex (mhc)-encoded MHC class I and class II molecules present peptide fragments to T cells at every stage of their life (development, survival, persistence and activation). Thereby, these unusually polymorphic molecules critically influence susceptibility to autoimmune and infectious diseases. Here, we examine the mechanistic relationship between mhc polymorphism and anti-microbial resistance/susceptibility.

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