Potent antiviral agent WIN 54954: high specific activity labelling with tritium
- PMID: 15110350
- PMCID: PMC7127203
- DOI: 10.1016/j.apradiso.2004.03.002
Potent antiviral agent WIN 54954: high specific activity labelling with tritium
Abstract
Valuable antiviral compound WIN 54954 was tritiated at high specific activity and the product was characterized.
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References
-
- Diana G.D., Cutcliffe D., Oglesby R.C., Otto M.J., Mallamo J.P., Akullian V., McKinlay M.A. Synthesis and structure-activity studies on some disubstituted phenylisoxazoles against human picornavirus. J. Med. Chem. 1989;32:450–455. - PubMed
-
- Filer C.N., Ahern D.G. The synthesis of glycine receptor radioligands [21,22-3H] dihydrostrychnine and [12-3H] strychnine at high specific activity. J. Labelled Comp. Radiopharm. 1989;27:309–318.
-
- Mallamo J.P., Diana G.D., Pevear D.C., Dutko F.J., Chapman M.S., Kim K.H., Minor I., Oliveira M., Rossmann M.G. Conformationally restricted analogues of disoxaril: a comparison of the activity against human rhinovirus types 14 and 1A. J. Med. Chem. 1992;35:4690–4695. - PubMed
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