Natural product glycorandomization
- PMID: 15112655
- DOI: 10.1016/j.bmc.2003.12.046
Natural product glycorandomization
Abstract
glycorandomization is a chemoenzymatic strategy that overcomes the limitations in natural product derivatization associated with both solely chemistry-based approaches or in vivo engineering. In this article we present the basic strategies for glycorandomization development as a next-generation tool in drug discovery.
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