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Review
. 2004 Apr 1;12(7):1577-84.
doi: 10.1016/j.bmc.2003.12.046.

Natural product glycorandomization

Jie Yang  1 , Dirk Hoffmeister, Lesley Liu, Xun Fu, Jon S Thorson
Affiliations
Review

Natural product glycorandomization

Jie Yang et al. Bioorg Med Chem. .

Abstract

glycorandomization is a chemoenzymatic strategy that overcomes the limitations in natural product derivatization associated with both solely chemistry-based approaches or in vivo engineering. In this article we present the basic strategies for glycorandomization development as a next-generation tool in drug discovery.

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