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Comment
. 2004 Jan;11(1):3-4.
doi: 10.1016/j.chembiol.2004.01.010.

Grafting miniature DNA binding proteins

Mary Kay H Pflum  1
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Free article
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Grafting miniature DNA binding proteins

Mary Kay H Pflum. Chem Biol. 2004 Jan.
Free article

Abstract

Miniature proteins serve as leads for biological and medicinal applications by positioning all amino acids necessary for biomolecular recognition on a compact protein structure. Protein grafting was recently used to create miniature helical proteins with high DNA binding affinity and specificity.

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