Review
doi: 10.1016/j.cub.2004.04.024.
Molecular evolution: introns fall into place
Affiliations
- PMID: 15120089
- DOI: 10.1016/j.cub.2004.04.024
Item in Clipboard
Review
Molecular evolution: introns fall into place
Curr Biol.
.
Free article
Abstract
The evolutionary origin of spliceosomal introns remains elusive. The startling success of a new way of predicting intron sites suggests that the splicing machinery determines where introns are added to genes.
Comment on
-
Exon junction sequences as cryptic splice sites: implications for intron origin.Curr Biol. 2004 Mar 23;14(6):505-9. doi: 10.1016/j.cub.2004.02.063. Curr Biol. 2004. PMID: 15043816
Similar articles
-
Changes in exon-intron structure during vertebrate evolution affect the splicing pattern of exons.Genome Res. 2012 Jan;22(1):35-50. doi: 10.1101/gr.119834.110. Epub 2011 Oct 5. Genome Res. 2012. PMID: 21974994 Free PMC article.
-
The low information content of Neurospora splicing signals: implications for RNA splicing and intron origin.RNA. 2015 May;21(5):997-1004. doi: 10.1261/rna.047985.114. Epub 2015 Mar 24. RNA. 2015. PMID: 25805857 Free PMC article.
-
Differential GC content between exons and introns establishes distinct strategies of splice-site recognition.Cell Rep. 2012 May 31;1(5):543-56. doi: 10.1016/j.celrep.2012.03.013. Epub 2012 May 3. Cell Rep. 2012. PMID: 22832277
-
The evolution of spliceosomal introns: patterns, puzzles and progress.Nat Rev Genet. 2006 Mar;7(3):211-21. doi: 10.1038/nrg1807. Nat Rev Genet. 2006. PMID: 16485020 Review.
-
Coevolution of genomic intron number and splice sites.Trends Genet. 2007 Jul;23(7):321-5. doi: 10.1016/j.tig.2007.04.001. Epub 2007 Apr 18. Trends Genet. 2007. PMID: 17442445 Review.
Cited by
-
Worm genomes hold the smoking guns of intron gain.Proc Natl Acad Sci U S A. 2004 Aug 3;101(31):11195-6. doi: 10.1073/pnas.0404148101. Epub 2004 Jul 26. Proc Natl Acad Sci U S A. 2004. PMID: 15277668 Free PMC article. Review. No abstract available.
-
Synonymous Codon Usage Bias in the Plastid Genome is Unrelated to Gene Structure and Shows Evolutionary Heterogeneity.Evol Bioinform Online. 2015 Apr 7;11:65-77. doi: 10.4137/EBO.S22566. eCollection 2015. Evol Bioinform Online. 2015. PMID: 25922569 Free PMC article.
-
Defective splicing, disease and therapy: searching for master checkpoints in exon definition.Nucleic Acids Res. 2006 Jul 19;34(12):3494-510. doi: 10.1093/nar/gkl498. Print 2006. Nucleic Acids Res. 2006. PMID: 16855287 Free PMC article. Review.
-
Synonymous codon usage bias is correlative to intron number and shows disequilibrium among exons in plants.BMC Genomics. 2013 Jan 28;14:56. doi: 10.1186/1471-2164-14-56. BMC Genomics. 2013. PMID: 23350908 Free PMC article.
-
The Shift in Synonymous Codon Usage Reveals Similar Genomic Variation during Domestication of Asian and African Rice.Int J Mol Sci. 2022 Oct 25;23(21):12860. doi: 10.3390/ijms232112860. Int J Mol Sci. 2022. PMID: 36361651 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
