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Review
. 2004 Feb;18(1):59-80.
doi: 10.1016/j.berh.2003.09.010.

The transfer of a laboratory based hypothesis to a clinically useful therapy: the development of anti-TNF therapy of rheumatoid arthritis

Marc Feldmann  1 , Fionula M Brennan, Richard O Williams, James N Woody, Ravinder N Maini
Affiliations
Review

The transfer of a laboratory based hypothesis to a clinically useful therapy: the development of anti-TNF therapy of rheumatoid arthritis

Marc Feldmann et al. Best Pract Res Clin Rheumatol. 2004 Feb.

Abstract

The development of anti-TNF therapy is a key step forward in rheumatology as it is the first new therapy for based on investigating the molecular mechanisms of this disease. This chapter reviews how this discovery was made.

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