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Multicenter Study
. 2004 May:184:386-92.
doi: 10.1192/bjp.184.5.386.

Global burden of depressive disorders in the year 2000

T B Ustün  1 , J L Ayuso-Mateos, S Chatterji, C Mathers, C J L Murray
Affiliations
Multicenter Study

Global burden of depressive disorders in the year 2000

T B Ustün et al. Br J Psychiatry. 2004 May.

Abstract

Background: The initial Global Burden of Disease study found that depression was the fourth leading cause of disease burden, accounting for 3.7% of total disability adjusted life years (DALYs) in the world in 1990.

Aims: To present the new estimates of depression burden for the year 2000.

Method: DALYs for depressive disorders in each world region were calculated, based on new estimates of mortality, prevalence, incidence, average age at onset, duration and disability severity.

Results: Depression is the fourth leading cause of disease burden, accounting for 4.4% of total DALYs in the year 2000, and it causes the largest amount of non-fatal burden, accounting for almost 12% of all total years lived with disability worldwide.

Conclusions: These data on the burden of depression worldwide represent a major public health problem that affects patients and society.

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