All systems go
- PMID: 15123734
- PMCID: PMC2172193
- DOI: 10.1083/jcb.200404013
All systems go
Abstract
Reductionism has served cell biologists well in the past decades, but systems biologists are now promising to broaden the picture. The challenge will be to provide not just the lists and quantitation but real mechanistic insights.
Copyright the Rockefeller University Press
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References
-
- Alon, U., M.G. Surette, N. Barkai, and S. Leibler. 1999. Robustness in bacterial chemotaxis. Nature. 397:168–171. - PubMed
-
- Chahwala, S.B., L.F. Flieschman, and L. Cantley. 1987. Kinetic analysis of guanosine 5′-O-(3-thiotriphosphate) effects on phosphatidylinositol turnover in NRK cell homogenates. Biochemistry. 26:612–622. - PubMed
-
- Cluzel, P., M. Surette, and S. Leibler. 2000. An ultrasensitive bacterial motor revealed by monitoring signaling proteins in single cells. Science. 287:1652–1655. - PubMed
-
- Elowitz, M.B., A.J. Levine, E.D. Siggia, and P.S. Swain. 2002. Stochastic gene expression in a single cell. Science. 297:1183–1186. - PubMed
-
- Korobkova, E., T. Emonet, J.M.G. Vilar, T.S. Shimizu, and P. Cluzel. 2004. From molecular noise to behavioural variability in a single bacterium. Nature. 428:574–578. - PubMed
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