[Current progress of matrix metalloproteinase in acute lung injury following cardiopulmonary bypass]
- PMID: 15127595
[Current progress of matrix metalloproteinase in acute lung injury following cardiopulmonary bypass]
Abstract
Degradation of basement membrane of pulmonary capillaries was the main pathological feature of lung injury following cardiopulmonary bypass (CPB). Matrix metalloproteinases (MMPs) contributed to the development of lung injury following CPB via degrading extracellular matrix and regulating cytokines. So, understanding the effects of MMPs in the lung injury following CPB may be helpful to prevent and treat the complications mentioned above.
Similar articles
-
A rise of MMP-2 and MMP-9 in bronchoalveolar lavage fluid is associated with acute lung injury after cardiopulmonary bypass in a swine model.Perfusion. 2003 Apr;18(2):107-13. doi: 10.1191/0267659103pf662oa. Perfusion. 2003. PMID: 12868788
-
Ultrastructural changes in the lung alveoli after cardiac surgical operations with the use of cardiopulmonary bypass (CPB).Pol J Pathol. 1999;50(3):189-96. Pol J Pathol. 1999. PMID: 10624121
-
Matrix metalloproteinases in acute lung injury: mediators of injury and drivers of repair.Eur Respir J. 2011 Oct;38(4):959-70. doi: 10.1183/09031936.00032111. Epub 2011 May 12. Eur Respir J. 2011. PMID: 21565917 Review.
-
Matrix metalloproteinases and matrix metalloproteinase inhibitors in acute lung injury.Hum Pathol. 2006 Apr;37(4):422-30. doi: 10.1016/j.humpath.2005.11.023. Hum Pathol. 2006. PMID: 16564916
-
[Current progress of matrix metalloproteinases in systemic inflammatory reaction following cardiopulmonary bypass].Sheng Li Ke Xue Jin Zhan. 2011 Apr;42(2):145-7. Sheng Li Ke Xue Jin Zhan. 2011. PMID: 21770267 Review. Chinese. No abstract available.