Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2004 Jun;6(3):236-40.
doi: 10.1007/s11906-004-0075-8.

Leptin, sympathetic nervous system, and baroreflex function

Guido Grassi  1
Affiliations
Review

Leptin, sympathetic nervous system, and baroreflex function

Guido Grassi. Curr Hypertens Rep. 2004 Jun.

Abstract

In addition to its direct effects on energy metabolism and caloric intake, leptin exerts several circulatory effects that appear to be mediated by an interaction with the sympathetic nervous system and the major reflexogenic area involved in cardiovascular homeostatic control--that is, the arterial baroreflex. In this paper, the relationships between the adipocyte hormone and the neuroadrenergic function are reviewed, taking into account data collected in experimental animal models as well as in human cardiovascular (hypertension and heart failure) and noncardiovascular (obesity) diseases that are characterized by a hyperadrenergic state coupled with a hyperleptinemia.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. J Hypertens. 2002 Aug;20(8):1633-41 - PubMed
    1. Hypertension. 1998 Jan;31(1 Pt 2):409-14 - PubMed
    1. Circulation. 1994 Jun;89(6):2634-40 - PubMed
    1. J Clin Endocrinol Metab. 1998 May;83(5):1407-13 - PubMed
    1. J Clin Endocrinol Metab. 2000 May;85(5):1810-4 - PubMed