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Review
. 2003 Dec:16 Suppl 2:S17-22.
doi: 10.1097/00019052-200312002-00004.

Dopamine and cognitive function

Bernard Pillon  1 , Virginie Czernecki, Bruno Dubois
Affiliations
Review

Dopamine and cognitive function

Bernard Pillon et al. Curr Opin Neurol. 2003 Dec.

Abstract

Purpose of review: Although the cognitive deficits of idiopathic Parkinson's disease are now relatively well known, their neuropsychological and neurobiological basis are still discussed.

Recent findings: As well as recent findings on cognitive changes and their underlying mechanisms, we will review new approaches concerning the effects of levo-dihydroxyphenylalanine, those of deep-brain stimulation and recent developments on personality disorders.

Summary: Future research directions concern the relative influence of the striatofrontal loops in cognition and personality, and the respective contribution of subcortical and cortical lesions or dysfunctions, both in dementia and in specific cognitive and personality changes.

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