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Comparative Study
. 2004 May;11(3):618-20.
doi: 10.1128/CDLI.11.3.618-620.2004.

Evaluation of commercial immunoassays for detection of antibody against Helicobacter pylori in Thai dyspeptic patients

Orrawadee Hanvivatvong  1 , Atinop Pongpanich, Duangporn Thong-Ngam, Niramol Thammacharoenrach, Pinit Kullavanijaya
Affiliations
Comparative Study

Evaluation of commercial immunoassays for detection of antibody against Helicobacter pylori in Thai dyspeptic patients

Orrawadee Hanvivatvong et al. Clin Diagn Lab Immunol. 2004 May.

Abstract

The performance of five immunoassays for detection of immunoglobulin G antibody against Helicobacter pylori in 191 dyspeptic patients was evaluated. The sensitivities, specificities, accuracies, positive predictive values, and negative predictive values ranged from 86.32 to 97.89%, 57.95 to 72.22%, 77.02 to 83.76%, 71.54 to 77.42%, and 83.33 to 96.23%, respectively. The immunoglobulin A test kit also gave a high sensitivity and negative predictive value (95.79 and 91.40%, respectively), while the specificity was relatively low (51.14%).

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Figures

FIG. 1.
FIG. 1.
Distribution of anti-H. pylori IgG antibody levels in H. pylori-infected and uninfected patients (n = 191). Results of the Cobas Core anti-H. pylori EIA test, with serum antibody levels of <6 U/ml, were considered negative.
See this image and copyright information in PMC

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