Chemotherapy in metastatic gastric cancer: population-based perceptions and practice patterns of medical oncologists
- PMID: 15138466
- PMCID: PMC2409478
- DOI: 10.1038/sj.bjc.6601802
Chemotherapy in metastatic gastric cancer: population-based perceptions and practice patterns of medical oncologists
Abstract
Although randomised trials in metastatic gastric cancer have shown a survival benefit from chemotherapy, a significant proportion of medical oncologists do not believe that it prolongs survival or improves quality of life, including those who routinely treat metastatic gastric cancer. There was wide variation in what was considered to be 'standard therapy' and a statistically significant difference between what medical oncologists consider 'standard therapy' and what they use in every day practice.
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References
-
- Ajani JA (2000) Standard chemotherapy for gastric carcinoma: is it a myth? J Clin Oncol 18: 4001–4003 - PubMed
-
- Consensus Statement (1990) Cytostatic Drug Treatment in Advanced Cancer. Stockholm: MFR Spri
-
- Cullinan SA, Moertel CG, Fleming TR, Rubin JR, Krook JE, Everson LK, Windschitl HE, Twito DI, Marschke RF, Foley JF, Pfeifle DM, Barlow JF (1985) A comparison of three chemotherapeutic regimens in the treatment of advanced pancreatic and gastric carcinoma. Fluorouracil vs fluorouracil and doxorubicin vs fluorouracil, doxorubicin, and mitomycin. JAMA 253: 2061–2067 - PubMed
-
- di Bartolomeo M, Bajetta E, de Braud F, Bochicchio AM, Gebbia V, Bozzetti F, Doci R, Bonfanti G, Cozzaglio L (1995) Phase II study of the etoposide, leucovorin and fluorouracil combination for patients with advanced gastric cancer unsuitable for aggressive chemotherapy. Oncology 52: 41–44 - PubMed
-
- Findlay M, Cunningham D, Norman A, Mansi J, Nicolson M, Hickish T, Nicolson V, Nash A, Sacks N, Ford H, Carter R, Hill A (1994) A phase II study in advanced gastro-esophageal cancer using epirubicin and cisplatin in combination with continuous infusion fluorouracil (ECF). Ann Oncol 5: 609–616 - PubMed
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