Review
doi: 10.1016/j.ceb.2004.03.012.
The ever-increasing complexities of the exon junction complex
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- PMID: 15145352
- DOI: 10.1016/j.ceb.2004.03.012
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Review
The ever-increasing complexities of the exon junction complex
Curr Opin Cell Biol.
2004 Jun.
Abstract
Over the past decade many studies have revealed a complex web of interconnections between the numerous steps required for eukaryotic gene expression. One set of interconnections link nuclear pre-mRNA splicing and the subsequent metabolism of the spliced mRNAs. It is now apparent that the means of connection is a set of proteins, collectively called the exon junction complex, which are deposited as a consequence of splicing upstream of mRNA exon-exon junctions.
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