Review
[Advances in the research of sperm protein 17]
[Article in
Chinese]
Affiliations
- PMID: 15148930
Item in Clipboard
Review
[Advances in the research of sperm protein 17]
[Article in
Chinese]
Zhonghua Nan Ke Xue.
2004 Apr.
Abstract
Sperm protein 17 (Sp17) is a testis-specific protein involved in acrosome reaction in spermatozoa. However, the Sp17 gene has been recently detected in normal non-testis tissues and malignant neoplasias. Therefore Sp17 may be a potential target for immunocontraception and a suitable target for tumor immunotherapy. This paper reviews the advances in the protein characterization, expression and distribution, and biological function of Sp17 and its clinical research.
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