N-acetyl-beta-D-glucosaminidase activity in urine of dental personnel
- PMID: 15149892
- DOI: 10.1016/j.cccn.2004.02.028
N-acetyl-beta-D-glucosaminidase activity in urine of dental personnel
Abstract
Background: Dental personnel is exposed to several potential nephrotoxic agents. Urinary N-acetyl-beta-d-glucosaminidase (U-NAG) activity has emerged as a sensitive marker of early nephrotoxicity.
Methods: U-NAG was evaluated, by fluorimetric assay, in urine from 30 healthy subjects and 30 dental personnels.
Results: The median value of U-NAG activity (133.5 U/mmol urinary creatinine (U-Cr) in urines of dental personnel was not statistically different (P>0.05) from activity (100.7 U/mmol U-Cr) of control urines.
Conclusions: The results suggest that, for dental personnel, exposure to potential nephrotoxic agents is not usually high enough to increase U-NAG activity.
Copyright 2004 Elsevier B.V.
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