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Review
. 2004 Aug;43(8):949-54.
doi: 10.1093/rheumatology/keh225. Epub 2004 May 18.

Poststreptococcal reactive arthritis: what is it and how do we know?

S L Mackie  1 , A Keat
Affiliations
Review

Poststreptococcal reactive arthritis: what is it and how do we know?

S L Mackie et al. Rheumatology (Oxford). 2004 Aug.

Abstract

Objective: To find out whether poststreptococcal reactive arthritis (PSRA) is a discrete, homogeneous clinical syndrome.

Method: Literature review from case reports and case series.

Results: One hundred and eighty-eight cases were identified. The age distribution was bimodal, with one peak in childhood and one peak in adulthood. Eighty-three percent of streptococcal isolates were group A. The clinical presentation was heterogeneous but appeared different both from that of acute rheumatic fever (ARF) and from that of HLA B27-associated reactive arthritis. Carditis was rare.

Conclusions: The term PSRA encompasses significant heterogeneity. The link between the arthritis and the streptococcal infection is unproven.

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