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. 2004 Jun;48(6):2334-6.
doi: 10.1128/AAC.48.6.2334-2336.2004.

IMP-1 and a novel metallo-beta-lactamase, VIM-6, in fluorescent pseudomonads isolated in Singapore

Tse Hsien Koh  1 , Grace Chee Yeng Wang, Li-Hwei Sng
Affiliations

IMP-1 and a novel metallo-beta-lactamase, VIM-6, in fluorescent pseudomonads isolated in Singapore

Tse Hsien Koh et al. Antimicrob Agents Chemother. 2004 Jun.

Abstract

Four carbapenem-resistant Pseudomonas spp. were isolated from patients in Singapore. One Pseudomonas putida isolate contained a bla(IMP-1) identical to that first described in Japan. The sequence of a variant bla(IMP-1) in Pseudomonas fluorescens contained four silent mutations compared with the original sequence. The remaining P. putida isolates contained bla(VIM-6), a novel VIM gene variant.

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Figures

FIG. 1.
FIG. 1.
Comparison of the amino acid sequences of VIM β-lactamases. Amino acids which distinguish the VIM-2 cluster are highlighted. (asterisks, identical residues; colons, conserved substitutions; dots, semiconserved substitutions.
See this image and copyright information in PMC

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