Review
doi: 10.1016/j.micinf.2004.02.012.
What kind of message does IL-12/IL-23 bring to macrophages and dendritic cells?
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- PMID: 15158199
- DOI: 10.1016/j.micinf.2004.02.012
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Review
What kind of message does IL-12/IL-23 bring to macrophages and dendritic cells?
Microbes Infect.
2004 May.
Free article
Abstract
The present review illustrates the current knowledge on the autocrine effect of IL-12, and the putative contribution of IL-23, on macrophages and dendritic cells, focusing on cell activation and microbicidal activity. Here, we present convincing evidence that IL-12 is not only a connective element between accessory cells and lymphocytes, but it is also a key molecule for programming the macrophage and dendritic cell functions.
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