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Comment
. 2004 May 28;117(5):555-6.
doi: 10.1016/j.cell.2004.05.005.

Checkpoint adaptation; molecular mechanisms uncovered

Patrick J Lupardus  1 , Karlene A Cimprich
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Checkpoint adaptation; molecular mechanisms uncovered

Patrick J Lupardus et al. Cell. .
Free article

Abstract

Adaptation to the DNA damage checkpoint is a phenomenon long thought to be confined to the unicellular world. A new report in this issue of Cell by suggests the presence of a checkpoint adaptation pathway in Xenopus egg extracts that displays interesting molecular parallels to adaptation in yeast.

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