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Review
. 2004 Jun;49(6):640-52.

Aerosolized prostacyclins

Affiliations
  • PMID: 15165299
Review

Aerosolized prostacyclins

Mark Siobal. Respir Care. 2004 Jun.

Abstract

Two prostacyclins (prostaglandin E(1) and prostaglandin I(2)) are potent vasodilators. Aerosolized prostacyclins reduce pulmonary artery pressure, improve right heart function, and increase arterial oxygenation by improving ventilation/perfusion matching. This report describes aerosolized prostacyclins and compares them to inhaled nitric oxide. I review the types of inhalable prostacyclins and their indications, evidence of efficacy, delivery, and adverse effects.

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